RISK OF HORMONE ESCAPE IN A HUMAN PROSTATE CANCER MODEL DEPENDS ON THERAPY MODALITIES AND CAN BE REDUCED BY TYROSINE KINASE INHIBITORS.

Risk of hormone escape in a human prostate cancer model depends on therapy modalities and can be reduced by tyrosine kinase inhibitors.

Almost all prostate cancers respond to androgen deprivation treatment but many recur.We postulated that risk of hormone escape--frequency and delay--are influenced by hormone therapy modalities.More, hormone therapies induce crucial biological changes involving androgen receptors; some might be targets for escape prevention.We investigated the rela

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Eye movement desensitisation and reprocessing (EMDR) treatment associated with parent management training (PMT) for the acute symptoms in a patient with PANDAS syndrome: a case report

Abstract Background The purpose of this report was to present the results of eye movement desensitisation and reprocessing (EMDR) therapy associated with parent management training (PMT) in a child with paediatric autoimmune neuropsychiatric disorder WILD STYLERS DEPOLISH associated with streptococcus (PANDAS), who had previously only been treated

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CRITERIA FOR QUALITATIVE ASSESSMENT OF INDICATORS OF THE IMPACT OF PLANNED ACTIVITIES ON THE STATE OF THE ENVIRONMENT

In order to assess HEART FORMULA the impact of planned activities on the environment of mining enterprises, it is necessary to realize that the impact factors are very diverse in terms of characteristics.Therefore, during the preparation of Environmental Impact Assessment Reports of planned activities, developers are faced with the problem of defin

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Metabolomic profiling reveals a differential role for hippocampal glutathione reductase in infantile memory formation

The metabolic mechanisms underlying the formation of early-life episodic memories remain poorly characterized.Here, we assessed the metabolomic profile of the rat hippocampus at different developmental ages both at baseline and following episodic learning.We report that the hippocampal metabolome significantly changes over developmental ages and th

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